Patogénesis de dengue: consideraciones moleculares.

Main Article Content

Eduardo Tarquino Jurado Cobeña
Mary Ernestina Regato Arrata

Abstract

El virus dengue es el arbovirus de mayor importancia a nivel mundial; alrededor de 2 500 millones de personas viven en más de 100 países endémicos. Hasta 50 millones de infecciones ocurren anualmente con 500 000 casos de fiebre hemorrágica por dengue y 22 000 muertes principalmente entre niños. En el Ecuador el dengue es una enfermedad endémica y los cuatro serotipos se encuentran circulando. Este trabajo hace una breve revisión bibliográfica de las bases moleculares de la patogenicidad; así como también de las interacciones inmunológicas moleculares virus-huésped, haciendo énfasis en los hallazgos más importantes tanto a nivel experimental cuanto a nivel clínico, finalmente se discuten las perspectivas del conocimiento actual.

Article Details

How to Cite
1.
Jurado Cobeña ET, Regato Arrata ME. Patogénesis de dengue: consideraciones moleculares. Rev. Med. UCSG [Internet]. 2016 Jan. 21 [cited 2024 Nov. 24];19(1):58-65. Available from: https://editorial.ucsg.edu.ec/medicina/index.php/ucsg-medicina/article/view/742
Section
Artículos de Revisión
Author Biographies

Eduardo Tarquino Jurado Cobeña, Instituto Nacional de Investigación en Salud Pública, INSPI

Responsable de la Plataforma de Genómica/Investigador del Centro de Referencia Nacional de Dengue y otros Arbovirus

Mary Ernestina Regato Arrata, Instituto Nacional de Investigación en Salud Pública, INSPI

Responsable del Centro de Referencia Nacional de Dengue y otros Arbovirus

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