Patogénesis de dengue: consideraciones moleculares.

Contenido principal del artículo

Eduardo Tarquino Jurado Cobeña
Mary Ernestina Regato Arrata

Resumen

El virus dengue es el arbovirus de mayor importancia a nivel mundial; alrededor de 2 500 millones de personas viven en más de 100 países endémicos. Hasta 50 millones de infecciones ocurren anualmente con 500 000 casos de fiebre hemorrágica por dengue y 22 000 muertes principalmente entre niños. En el Ecuador el dengue es una enfermedad endémica y los cuatro serotipos se encuentran circulando. Este trabajo hace una breve revisión bibliográfica de las bases moleculares de la patogenicidad; así como también de las interacciones inmunológicas moleculares virus-huésped, haciendo énfasis en los hallazgos más importantes tanto a nivel experimental cuanto a nivel clínico, finalmente se discuten las perspectivas del conocimiento actual.

Detalles del artículo

Cómo citar
1.
Jurado Cobeña ET, Regato Arrata ME. Patogénesis de dengue: consideraciones moleculares. Rev. Med. UCSG [Internet]. 21 de enero de 2016 [citado 28 de marzo de 2024];19(1):58-65. Disponible en: https://editorial.ucsg.edu.ec/ojs-medicina/index.php/ucsg-medicina/article/view/742
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Biografía del autor/a

Eduardo Tarquino Jurado Cobeña, Instituto Nacional de Investigación en Salud Pública, INSPI

Responsable de la Plataforma de Genómica/Investigador del Centro de Referencia Nacional de Dengue y otros Arbovirus

Mary Ernestina Regato Arrata, Instituto Nacional de Investigación en Salud Pública, INSPI

Responsable del Centro de Referencia Nacional de Dengue y otros Arbovirus

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